About posaconaz ole
Triazole antifungal
Used for
- Prevents invasive fungal infections in people at high risk.
- Treats certain invasive fungal infections, including aspergillosis.
Usual adult dose
Prevention: 300 mg twice daily on day one, then 300 mg once daily. Treatment dosing varies by infection.
Usual dose in children
For children aged 2 years and older, dosing depends on weight and indication; specialist supervision is required.
Common side effects
- Nausea, vomiting, or diarrhea
- Headache
- Abnormal liver tests
- Low potassium
Important warnings
- Can cause serious liver problems; monitoring may be needed.
- May prolong the heart rhythm and cause serious arrhythmias.
- Many important drug interactions; some combinations are unsafe.
- Swallow tablets whole; do not crush or chew.
Pregnancy
Use only when clearly needed; human pregnancy information is limited, and animal studies found fetal harm.
Breastfeeding
It is unknown whether posaconazole passes into breast milk; discuss risks with a healthcare professional.
Interactions
- Certain statins, ergot medicines, and sirolimus can reach dangerous levels.
- May interact with some antiarrhythmics and medicines that prolong heart rhythm.
- Rifampicin, rifabutin, and some seizure medicines can reduce posaconazole levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.