About poly
Colloid plasma volume expander
Used for
- Replacing blood volume after acute blood loss when crystalloids are insufficient
Usual adult dose
Usually 500–1,000 mL intravenously; maximum 20 mL/kg daily. Use the lowest effective dose for no longer than 24 hours.
Common side effects
- Kidney injury
- Bleeding and impaired blood clotting
- Persistent itching
- Severe allergic reactions
Important warnings
- Increased risk of kidney failure and death in critically ill patients
- Avoid in sepsis, burns, kidney impairment, or severe liver disease
- Can cause fluid overload; requires kidney, clotting, and fluid monitoring
- Suspended or restricted in many countries because of serious safety risks
Pregnancy
Safety is not established. Use only when the expected benefit clearly outweighs potential risks.
Breastfeeding
Transfer into breast milk and effects on infants are unknown.
Interactions
- Aminoglycoside antibiotics may increase kidney injury risk
- Anticoagulants and antiplatelet medicines may increase bleeding risk
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.