About podophyllin
Antimitotic topical agent
Used for
- Historically used on external genital warts; use is limited because safer treatments are available.
Usual adult dose
Applied by a clinician to warts, then washed off after 1–4 hours; repeat weekly if needed.
Common side effects
- Burning, pain, redness, or sores at the application site.
- Skin absorption can cause severe poisoning, including nerve, blood, kidney, or liver problems.
Important warnings
- For external use only; never apply internally or to large, bleeding, or damaged areas.
- Avoid use during pregnancy; poisoning can be life-threatening.
- Use only under clinician supervision; wash off at the specified time.
- Compounded preparations vary in concentration and may be hazardous if swallowed or absorbed.
Pregnancy
Avoid; podophyllin can harm the fetus.
Breastfeeding
Avoid because absorption and infant risk are uncertain; prevent infant contact with treated skin.
Interactions
- Other medicines applied to the same area may increase irritation or absorption.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.