About pizotifen malate
Serotonin antagonist antihistamine
Used for
- Prevention of migraine attacks
- Prevention of recurrent cluster headaches in some settings
Usual adult dose
Migraine prevention: usually 0.5 mg at night initially, increased gradually; typical total is 1.5 mg daily in divided doses.
Usual dose in children
For children aged 2 years and older: usually 0.5 mg at night initially, increased gradually; dosing depends on age and local guidance.
Common side effects
- Increased appetite and weight gain
- Drowsiness, dizziness, or tiredness
- Dry mouth
- Nausea or constipation
Important warnings
- Not for treating an active migraine attack
- May cause drowsiness; avoid driving if affected
- Use cautiously with glaucoma or urinary retention
- Do not stop suddenly after regular use without medical guidance
Pregnancy
Use only when clearly needed; discuss risks with a healthcare professional, as pregnancy data are limited.
Breastfeeding
May pass into breast milk and could cause drowsiness in the infant; use requires professional guidance.
Interactions
- Alcohol and sedatives can increase drowsiness
- Other antihistamines may increase drowsiness
- Some antidepressants may increase side effects
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.