About pizotifen
Serotonin antagonist antihistamine
Used for
- Prevention of migraine and recurrent vascular headaches
- Sometimes used to stimulate appetite
Usual adult dose
Migraine prevention: usually 0.5 mg at bedtime initially, gradually increased; typical maintenance is 1.5 mg daily in divided doses.
Usual dose in children
For ages 2–12: often started at 0.5 mg daily; adjusted gradually, usually up to 1.5 mg daily in divided doses.
Common side effects
- Sleepiness and fatigue
- Increased appetite and weight gain
- Dry mouth
- Dizziness or nausea
Important warnings
- May impair alertness; avoid driving if affected.
- Use cautiously with glaucoma, urinary retention, or kidney problems.
- Do not stop regular treatment suddenly without medical guidance.
- Not for stopping an ongoing migraine attack.
Pregnancy
Use only when clearly needed; pregnancy safety information is limited.
Breastfeeding
May pass into breast milk and can cause infant drowsiness; use requires clinical review.
Interactions
- Alcohol and sedatives can increase sleepiness.
- Other medicines causing drowsiness may increase impairment.
- Some medicines affecting liver enzymes can alter pizotifen levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.