About pizotifen
Serotonin antagonist antihistamine
Used for
- Prevention of migraine attacks
- Prevention of recurrent cluster headaches in some countries
Usual adult dose
Migraine prevention: usually 0.5 mg at night initially, increased gradually; common maintenance is 1.5 mg daily in divided doses.
Usual dose in children
For migraine prevention in children over 2 years: usually 0.5 mg daily initially, increased gradually; doses vary by age and local guidance.
Common side effects
- Increased appetite and weight gain
- Drowsiness, dizziness, or fatigue
- Dry mouth or nausea
- Constipation
Important warnings
- May cause drowsiness; avoid driving if affected.
- Use caution with glaucoma, urinary retention, or liver problems.
- Do not stop long-term treatment suddenly without medical guidance.
- Not for treating an ongoing migraine attack.
Pregnancy
Pregnancy safety information is limited; use only when a clinician considers it necessary.
Breastfeeding
May pass into breast milk; breastfeeding safety is uncertain.
Interactions
- Alcohol and sedatives can increase drowsiness.
- Other medicines causing drowsiness may intensify this effect.
- Some medicines affecting liver enzymes may alter pizotifen levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.