About piribedil
Dopamine agonist
Used for
- Parkinson’s disease, alone or with other medicines.
- Symptoms of chronic cognitive impairment in some countries.
Usual adult dose
Parkinson’s disease: usually 150–250 mg daily, divided into doses, with gradual dose adjustment.
Common side effects
- Nausea, vomiting, or stomach discomfort.
- Dizziness, sleepiness, or sudden sleep episodes.
- Low blood pressure when standing.
- Confusion, hallucinations, or impulse-control problems.
Important warnings
- May cause sudden sleepiness; avoid driving if affected.
- Can cause low blood pressure, especially when standing.
- May trigger compulsive behaviors, such as gambling or shopping.
- Do not stop suddenly; dose reduction should be gradual.
Pregnancy
Use during pregnancy is generally avoided unless clearly necessary; human safety information is limited.
Breastfeeding
Breastfeeding is generally not recommended because piribedil may reduce milk production and safety information is limited.
Interactions
- Antipsychotic medicines may reduce piribedil’s effect.
- Metoclopramide may reduce piribedil’s effect.
- Combining with other sedating medicines may increase sleepiness.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.