About piperacilli n m
Antipseudomonal penicillin plus beta-lactamase inhibitor
Used for
- Treatment of serious bacterial infections, including pneumonia and abdominal, skin, urinary, and bloodstream infections.
Usual adult dose
Usual adult dose is 3.375 g intravenously every 6 hours; dosing varies by infection and kidney function.
Usual dose in children
For children 2 months and older, dosing is based on weight and infection; kidney function affects dosing.
Common side effects
- Diarrhea, nausea, or vomiting
- Rash or allergic reactions
- Low blood cell counts
- Kidney or liver test changes
Important warnings
- Serious penicillin allergy can cause severe reactions.
- Dose adjustment may be needed with kidney impairment.
- Antibiotic-associated severe diarrhea can occur.
- Use only for infections caused by susceptible bacteria.
Pregnancy
Used during pregnancy when clinically needed; available evidence has not shown a clear increase in birth defects.
Breastfeeding
Small amounts may enter milk; infant diarrhea or thrush is possible.
Interactions
- Probenecid may increase antibiotic levels.
- Blood thinners may increase bleeding risk.
- Methotrexate levels may rise.
- May affect laboratory tests for glucose or blood clotting.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.