About phenprocumon
Vitamin K antagonist anticoagulant
Used for
- Prevention and treatment of blood clots
- Prevention of stroke in atrial fibrillation
- Prevention of clots with mechanical heart valves
Usual adult dose
Individualized; adjusted using regular INR tests. Often starts at 3–6 mg once daily, then varies by INR.
Usual dose in children
Specialist-directed, individualized by weight and INR; dosing varies widely.
Common side effects
- Bleeding or bruising
- Nausea or diarrhea
- Skin rash
- Rare skin or tissue damage
Important warnings
- Regular INR blood tests are essential.
- Many medicines, supplements, and dietary changes can alter its effect.
- Seek urgent care for serious bleeding or head injury.
- Do not stop or change dosing without clinical guidance.
Pregnancy
Can cause serious fetal harm and is generally avoided during pregnancy; specialist management is required.
Breastfeeding
Generally considered compatible with breastfeeding; monitor the infant for unusual bruising or bleeding.
Interactions
- NSAIDs and aspirin can increase bleeding.
- Antibiotics and antifungals may change INR.
- Vitamin K intake changes can alter anticoagulant effect.
- Herbal products, including St John's wort, may affect INR.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.