About perindopril arginine + indapamide
ACE inhibitor and thiazide-like diuretic
Used for
- Treats high blood pressure in adults when both medicines are needed.
Usual adult dose
Usual maintenance dose: one tablet once daily, taken in the morning; doses depend on prior treatment and kidney function.
Common side effects
- Dizziness or light-headedness
- Dry cough
- Low blood pressure
- Low potassium or sodium levels
Important warnings
- May impair kidney function or raise potassium; monitoring may be needed.
- Can cause severe allergic swelling, especially of the face, tongue, or throat.
- Avoid during pregnancy; stop promptly if pregnancy occurs.
- Use caution with dehydration, kidney disease, or significant liver disease.
Pregnancy
Not recommended; can seriously harm an unborn baby, particularly later in pregnancy.
Breastfeeding
Generally not recommended, especially for newborn or premature infants; seek an alternative with a clinician.
Interactions
- Lithium: may increase lithium levels and toxicity.
- NSAIDs, including ibuprofen: may worsen kidney function and reduce blood-pressure control.
- Potassium supplements or potassium-sparing medicines: may raise potassium.
- Other blood-pressure medicines or diuretics: may increase low blood pressure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.