About pentoxifyline
Methylxanthine blood-flow improving medicine
Used for
- Improves walking symptoms in peripheral arterial disease
Usual adult dose
Usually 400 mg three times daily with meals; may be reduced if poorly tolerated or kidney function is impaired.
Common side effects
- Nausea or indigestion
- Dizziness or headache
- Flushing
- Bleeding, rarely
Important warnings
- Use cautiously with bleeding disorders or recent surgery.
- Tell clinicians about a history of stomach ulcers or eye bleeding.
- Kidney or liver impairment may require a lower dose.
- Seek urgent care for signs of serious bleeding.
Pregnancy
Safety is not well established; use only when clearly needed and prescribed.
Breastfeeding
Information is limited; discuss use with a healthcare professional.
Interactions
- Blood thinners and antiplatelet medicines may increase bleeding risk.
- Blood pressure medicines may increase blood-pressure lowering.
- Theophylline levels may rise when taken together.
- Cimetidine may increase pentoxifylline levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.