About pasireotide
Somatostatin analogue
Used for
- Treats acromegaly when surgery or other medicines are unsuitable or ineffective.
- Treats Cushing’s disease when surgery is unsuitable or unsuccessful.
Usual adult dose
Acromegaly: usually 40 mg by deep intramuscular injection every 4 weeks, adjusted by response. Cushing’s disease: usually 10 mg every 4 weeks, adjusted by response.
Common side effects
- High blood sugar or diabetes
- Diarrhea, nausea, or abdominal pain
- Gallstones
- Slow heartbeat or changes in heart rhythm
Important warnings
- Blood sugar can rise substantially; glucose monitoring is required.
- Can cause gallstones and affect liver tests.
- May slow the heart or prolong the QT interval.
- Use caution with medicines that affect heart rhythm or blood sugar.
Pregnancy
Human pregnancy data are limited; use only when clearly needed, as treatment may affect hormones and fetal growth.
Breastfeeding
It is not known whether pasireotide passes into breast milk; breastfeeding is generally avoided during treatment.
Interactions
- Medicines that prolong QT interval may increase abnormal-heart-rhythm risk.
- Insulin and diabetes medicines may need adjustment as blood sugar changes.
- Strong CYP3A4 inhibitors can increase pasireotide exposure.
- Pasireotide may affect medicines whose levels depend on CYP3A4.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.