About pasireotid e
Somatostatin analogue
Used for
- Acromegaly when surgery or other medicines do not control the condition.
- Cushing disease when surgery is unsuitable or unsuccessful.
Usual adult dose
Acromegaly: 40 mg deep intramuscularly every 28 days, adjusted to response; Cushing disease: 10 mg every 28 days, adjusted to response.
Common side effects
- Raised blood sugar or diabetes
- Diarrhoea, nausea, or abdominal pain
- Gallstones
- Slow heart rate
Important warnings
- Monitor blood sugar before and during treatment; serious hyperglycaemia can occur.
- Liver tests, gallbladder checks, and heart rhythm monitoring may be needed.
- Can cause slow heart rate and affect heart rhythm.
- May reduce cortisol excessively when treating Cushing disease.
Pregnancy
Limited information; use during pregnancy only when clearly necessary. Treatment may restore fertility.
Breastfeeding
It is unknown whether pasireotide passes into breast milk; breastfeeding is generally avoided during treatment.
Interactions
- Medicines that slow heart rate, such as beta blockers, may increase bradycardia risk.
- Medicines that prolong the QT interval may increase abnormal heart rhythm risk.
- Pasireotide can affect medicines controlled by blood sugar, including insulin and diabetes tablets.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.