About paricalcitol
Vitamin D receptor activator
Used for
- Prevention and treatment of secondary hyperparathyroidism in chronic kidney disease, including dialysis patients.
Usual adult dose
IV: usually 0.04–0.1 micrograms/kg, given during dialysis three times weekly; adjusted to blood tests.
Usual dose in children
Used in children on dialysis: IV dosing is weight-based and adjusted to blood tests.
Common side effects
- High calcium or phosphate levels
- Nausea or vomiting
- Dizziness
- Swelling
Important warnings
- Monitor calcium, phosphate, and parathyroid hormone levels.
- Excess dosing can cause dangerously high calcium or phosphate.
- Use caution with kidney stones or abnormal heart rhythms.
Pregnancy
Use only when clearly needed; human pregnancy data are limited.
Breastfeeding
Unknown whether paricalcitol passes into breast milk; consider potential infant risks.
Interactions
- Other vitamin D products can increase calcium levels.
- Calcium supplements or thiazide diuretics may raise calcium.
- Phosphate binders can affect phosphate levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.