About paricalcit ol
Active vitamin D analogue
Used for
- Prevention and treatment of secondary hyperparathyroidism in adults with chronic kidney disease on hemodialysis.
Usual adult dose
Usually 0.04–0.1 micrograms/kg intravenously during dialysis, no more often than every other day; adjusted to blood test results.
Usual dose in children
Not established for routine use in children.
Common side effects
- Nausea
- Vomiting
- Swelling
- High calcium or phosphate levels
Important warnings
- Can raise calcium and phosphate; blood tests are needed during treatment.
- High calcium may cause confusion, weakness, constipation, or abnormal heart rhythm.
- Use caution with existing high calcium or vitamin D levels.
Pregnancy
Limited information; use only when a clinician considers it necessary.
Breastfeeding
Unknown whether paricalcitol passes into breast milk; clinical advice is needed.
Interactions
- Other vitamin D products can increase calcium levels.
- Thiazide diuretics may increase the risk of high calcium.
- Digoxin may increase heart rhythm risks if calcium becomes high.
- Phosphate binders containing calcium may increase calcium levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.