About parecoxib
Selective COX-2 inhibitor NSAID
Used for
- Short-term treatment of postoperative pain when injection is appropriate.
Usual adult dose
Usually 40 mg by injection, followed by 20 or 40 mg every 6–12 hours as needed; maximum 80 mg daily.
Common side effects
- Nausea
- Vomiting
- Headache
- Injection-site reactions
Important warnings
- Use the lowest effective dose for the shortest time.
- Avoid with serious kidney or liver problems, active ulcers, or NSAID allergy.
- May increase risk of heart attack, stroke, bleeding, or kidney problems.
- Not for treating pain before or during heart surgery.
Pregnancy
Avoid from 20 weeks unless specifically directed; contraindicated in the third trimester.
Breastfeeding
Human data are limited; use only if a clinician considers it necessary.
Interactions
- Blood thinners, including warfarin, may increase bleeding.
- Other NSAIDs increase ulcer, bleeding, and kidney risks.
- ACE inhibitors, ARBs, or diuretics may increase kidney risks.
- Fluconazole can increase parecoxib exposure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.