About parecoxib
Selective COX-2 inhibitor NSAID
Used for
- Short-term treatment of pain after surgery.
Usual adult dose
Usually 40 mg by injection initially, then 20 or 40 mg every 6–12 hours as needed; maximum 80 mg daily.
Common side effects
- Nausea or vomiting
- Headache or dizziness
- High blood pressure
- Injection-site reactions
Important warnings
- Can increase risks of heart attack, stroke, bleeding, and kidney problems.
- Avoid with allergy to sulfonamides, aspirin, or other NSAIDs.
- Not for use around coronary artery bypass surgery.
- Use the lowest effective dose for the shortest time.
Pregnancy
Avoid from 20 weeks unless specifically directed; avoid from 30 weeks because of fetal risks.
Breastfeeding
Breastfeeding information is limited; clinical guidance is needed before use.
Interactions
- Blood thinners may increase bleeding risk.
- ACE inhibitors, ARBs, and diuretics may increase kidney risks.
- Other NSAIDs increase side effects and should generally be avoided.
- Fluconazole can increase parecoxib exposure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.