About parathyroid hormone
Recombinant parathyroid hormone
Used for
- Adjunct treatment for adults with chronic hypoparathyroidism inadequately controlled with calcium and active vitamin D.
Usual adult dose
Start at 50 mcg under the skin once daily; adjust individually, usually 25–100 mcg daily.
Common side effects
- Low blood calcium
- High blood calcium
- Nausea or vomiting
- Injection-site reactions
Important warnings
- Risk of severe low blood calcium, especially after missed doses or stopping treatment.
- Blood calcium can become too high; monitoring and dose adjustment are needed.
- May increase osteosarcoma risk in animal studies; avoid in people at increased risk.
- Not for acute postoperative hypoparathyroidism or routine use in children.
Pregnancy
Human pregnancy data are limited; use only when potential benefit justifies potential risk.
Breastfeeding
It is unknown whether this medicine passes into human milk; effects on a nursing infant are unknown.
Interactions
- Digoxin: changes in blood calcium may increase risk of abnormal heart rhythms.
- Calcium supplements and active vitamin D may need adjustment as treatment changes.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.