About paraldehyde
Sedative and anticonvulsant
Used for
- Historically used for severe seizures, including status epilepticus.
- Historically used for severe agitation or delirium tremens.
Usual adult dose
Historical seizure dosing varied by route; no single standard dose. Injectable use requires specialist protocols.
Usual dose in children
Historical seizure dosing was weight-based and specialist-directed; no single standard dose.
Common side effects
- Drowsiness, dizziness, and impaired coordination
- Nausea, vomiting, and unpleasant breath odor
- Injection-site irritation or tissue damage
- Breathing suppression, especially with other sedatives
Important warnings
- Injectable paraldehyde is rarely used and may not be available.
- It can cause serious tissue injury if it leaks outside a vein.
- Avoid alcohol and other medicines that cause sedation.
- Use requires careful medical supervision and appropriate injection materials.
Pregnancy
Safety in pregnancy is not well established; use only when a specialist determines it is necessary.
Breastfeeding
Information is limited; potential effects on a nursing infant are uncertain.
Interactions
- Alcohol, opioids, and sedatives can increase drowsiness and breathing suppression.
- Medicines that affect liver enzymes may alter paraldehyde breakdown.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.