About acetaminophen usp
Non-opioid analgesic and antipyretic
Used for
- Relief of mild to moderate pain
- Reduction of fever
Usual adult dose
Usually 500–1000 mg every 4–6 hours as needed; maximum 4000 mg daily from all sources.
Usual dose in children
Usually 10–15 mg/kg every 4–6 hours; maximum 5 doses in 24 hours. Avoid adult tablets unless an appropriate dose can be measured.
Common side effects
- Usually few when taken correctly
- Rare serious allergic or skin reactions
- Liver damage, especially with overdose
Important warnings
- Do not combine with other medicines containing paracetamol.
- Excessive doses can cause life-threatening liver damage, sometimes without early symptoms.
- Use caution with liver disease, heavy alcohol use, or malnutrition.
Pregnancy
Generally considered suitable at recommended doses when needed; use the lowest effective dose for the shortest time.
Breastfeeding
Generally compatible with breastfeeding at recommended doses.
Interactions
- Warfarin: regular use may increase bleeding risk.
- Other paracetamol-containing medicines increase overdose risk.
- Some seizure medicines and rifampicin may increase liver toxicity risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.