About acetaminophen + tramadol hydrochloride
Opioid analgesic combination
Used for
- Short-term treatment of moderate to severe pain when other painkillers are inadequate.
Usual adult dose
Usually 1–2 tablets every 4–6 hours as needed; maximum 8 tablets daily. Follow the product leaflet or prescription.
Common side effects
- Nausea or vomiting
- Dizziness or sleepiness
- Constipation
- Headache
Important warnings
- Can cause dependence, misuse, and dangerous breathing problems.
- Avoid alcohol and driving if sleepy or dizzy.
- Do not combine with other paracetamol-containing medicines; overdose can severely damage the liver.
- Seizures and serotonin syndrome are possible, especially with certain medicines.
Pregnancy
Generally avoid during pregnancy unless a clinician determines it is necessary; prolonged use near delivery may affect the newborn.
Breastfeeding
Not recommended during breastfeeding because tramadol can cause serious breathing problems in a breastfed infant.
Interactions
- Alcohol, sedatives, and other opioids increase sleepiness and breathing risks.
- Antidepressants and other serotonin-raising medicines can increase serotonin syndrome or seizure risk.
- Warfarin may have increased bleeding risk with regular paracetamol use.
- Carbamazepine and some other medicines can alter tramadol’s effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.