About paliperidone
Atypical antipsychotic
Used for
- Schizophrenia
- Schizoaffective disorder
Usual adult dose
Schizophrenia: usually 6 mg once daily. Schizoaffective disorder: usually 6 mg once daily; range 3–12 mg.
Common side effects
- Sleepiness or dizziness
- Restlessness or movement problems
- Weight gain
- Increased prolactin, sometimes affecting periods or sexual function
Important warnings
- May increase risk of death in older adults with dementia-related psychosis.
- Can cause abnormal movements, high blood sugar, or changes in heart rhythm.
- Use caution with kidney problems; dose may need adjustment.
- Do not crush, chew, or split extended-release tablets.
Pregnancy
Use only when needed; exposure near delivery may cause newborn movement or withdrawal symptoms.
Breastfeeding
Paliperidone enters breast milk and may cause effects in a nursing infant.
Interactions
- Other medicines that cause sleepiness or lower blood pressure may increase these effects.
- Medicines affecting heart rhythm may increase heart-rhythm risks.
- Carbamazepine and other enzyme-inducing medicines can lower paliperidone levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.