About paliperido ne palmitate
Long-acting atypical antipsychotic
Used for
- Maintenance treatment of schizophrenia in adults who are stable on monthly or three-monthly paliperidone injections.
Usual adult dose
Given by a healthcare professional as a deep muscle injection every six months. The dose depends on the previous paliperidone injection regimen.
Common side effects
- Injection-site pain or lump
- Weight gain
- Sleepiness or restlessness
- Movement problems, including tremor or stiffness
Important warnings
- Can increase blood sugar, cholesterol, and prolactin levels.
- May cause tardive dyskinesia, a potentially persistent movement disorder.
- May cause dizziness or fainting, especially when standing.
- Not recommended for people with moderate or severe kidney impairment.
Pregnancy
Use during pregnancy only when clearly needed; exposure near delivery may cause newborn movement or withdrawal symptoms.
Breastfeeding
Paliperidone passes into breast milk; effects on a nursing infant are uncertain.
Interactions
- Other medicines that cause sleepiness or lower blood pressure may increase these effects.
- Medicines that prolong the QT interval can increase abnormal heart rhythm risk.
- Carbamazepine may lower paliperidone levels.
- Levodopa and dopamine agonists may have reduced effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.