About ondansetr on injection
Serotonin 5-HT3 receptor blocker
Used for
- Prevention or treatment of nausea and vomiting from surgery, chemotherapy, or radiotherapy
Usual adult dose
Commonly 4 mg by injection for postoperative nausea; chemotherapy dosing varies by regimen.
Usual dose in children
For postoperative nausea, commonly 0.1 mg/kg by injection, up to 4 mg.
Common side effects
- Headache
- Constipation
- Dizziness
- Injection-site discomfort
Important warnings
- May affect heart rhythm, especially with long QT syndrome or low potassium or magnesium.
- Seek urgent care for signs of a severe allergic reaction.
- Can cause serotonin syndrome, particularly with other serotonin-affecting medicines.
Pregnancy
Use only when clinically needed; evidence in pregnancy is limited, and risks should be assessed by a clinician.
Breastfeeding
Human milk data are limited; discuss use with a clinician.
Interactions
- Apomorphine: combination is contraindicated because of severe low blood pressure and loss of consciousness.
- Other medicines that prolong QT may increase abnormal heart rhythm risk.
- Serotonergic medicines may increase serotonin syndrome risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.