About omeprazole ph eur
Proton pump inhibitor
Used for
- Treats gastro-oesophageal reflux and related inflammation
- Treats stomach or duodenal ulcers
- Helps prevent ulcers caused by certain anti-inflammatory medicines
- Used with antibiotics to treat Helicobacter pylori infection
Usual adult dose
Usually 20 mg once daily for reflux or ulcers; dose and duration depend on condition.
Usual dose in children
For reflux, usually 0.7–3.5 mg/kg once daily, adjusted by weight and clinical response.
Common side effects
- Headache
- Abdominal pain, nausea, diarrhoea, or constipation
- Wind
- Skin rash
Important warnings
- Long-term use may lower magnesium or vitamin B12 levels and increase fracture risk.
- Rarely, severe allergic reactions, kidney inflammation, or serious skin reactions occur.
- Persistent diarrhoea may signal an intestinal infection.
- Can mask symptoms of stomach cancer; assessment may be needed before treatment.
Pregnancy
Available evidence has not shown a clear increased risk; use should be considered with a healthcare professional.
Breastfeeding
Omeprazole passes into breast milk in small amounts; it is generally considered compatible with breastfeeding.
Interactions
- Clopidogrel: omeprazole may reduce its antiplatelet effect.
- Warfarin: may alter anticoagulant effects; monitoring may be needed.
- Some HIV medicines, including nelfinavir, should not be combined.
- May affect absorption of medicines such as ketoconazole and iron.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.