About omeprazol
Proton pump inhibitor
Used for
- Short-term treatment of stomach or duodenal ulcers when oral treatment is unsuitable
- Treatment of reflux oesophagitis when oral treatment is unsuitable
- Prevention of acid aspiration during anaesthesia
- Treatment of excessive stomach acid, such as in Zollinger–Ellison syndrome
Usual adult dose
Usually 40 mg intravenously once daily; doses vary for some conditions.
Usual dose in children
Used in children aged 1 year and older when oral treatment is unsuitable; dose is weight-based, typically 10–20 mg once daily.
Common side effects
- Headache
- Abdominal pain, nausea, diarrhoea, or constipation
- Injection-site reactions
- Low magnesium with prolonged use
Important warnings
- Rarely, severe allergic or skin reactions occur.
- Prolonged use may increase fracture, intestinal infection, or vitamin B12 deficiency risks.
- May mask symptoms of stomach cancer.
- Dose adjustment may be needed with severe liver disease.
Pregnancy
Use only when clinically necessary; available information has not shown a clear increase in major birth defects.
Breastfeeding
Omeprazole passes into breast milk in small amounts; it is generally considered compatible with breastfeeding.
Interactions
- Clopidogrel: omeprazole may reduce its antiplatelet effect.
- Warfarin: may alter anticoagulant effect; monitoring may be needed.
- Some HIV medicines, including nelfinavir, should not be combined.
- May affect medicines whose absorption depends on stomach acidity.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.