About odevixibat
Ileal bile acid transport inhibitor
Used for
- Treats itching caused by progressive familial intrahepatic cholestasis (PFIC) in adults and children aged 3 months or older.
- Treats itching caused by Alagille syndrome in adults and children aged 12 months or older.
Usual adult dose
PFIC or Alagille syndrome: 40 micrograms/kg by mouth once daily; may increase to 120 micrograms/kg once daily if needed and tolerated.
Usual dose in children
Usually 40 micrograms/kg by mouth once daily; may increase to 120 micrograms/kg once daily if needed and tolerated. Age approvals vary by condition.
Common side effects
- Diarrhea
- Abdominal pain
- Vomiting
- Liver test abnormalities
Important warnings
- Monitor for diarrhea, dehydration, and worsening liver problems.
- Check liver tests before treatment and during treatment.
- May reduce absorption of fat-soluble vitamins; monitor and supplement as needed.
- Separate from bile acid-binding medicines by at least 4 hours.
Pregnancy
Human pregnancy information is limited. Use only when the expected benefit justifies potential risk.
Breastfeeding
It is unknown whether odevixibat passes into breast milk; effects on a nursing infant are unknown.
Interactions
- Bile acid-binding medicines can reduce absorption; separate doses by at least 4 hours.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.