About Obinut uzuma b 1000M G/40M
Anti-CD20 monoclonal antibody
Used for
- Chronic lymphocytic leukaemia, usually with other medicines
- Follicular lymphoma, with chemotherapy or other treatments
Usual adult dose
Usually 1,000 mg by intravenous infusion on scheduled treatment days; regimens vary by condition and treatment cycle.
Common side effects
- Infusion reactions, including fever, chills, or breathing problems
- Low blood cell counts
- Infections
- Nausea or diarrhoea
Important warnings
- Infusion reactions can be severe, especially with the first infusion.
- Can cause serious infections, including hepatitis B reactivation.
- Rarely causes progressive multifocal leukoencephalopathy, a serious brain infection.
- Tumour lysis syndrome may occur, particularly early in treatment.
Pregnancy
May harm an unborn baby. Effective contraception is recommended during treatment and for six months afterward.
Breastfeeding
Breastfeeding is not recommended during treatment and for six months after the last dose.
Interactions
- Other medicines that suppress the immune system may increase infection risk.
- Live vaccines should be avoided during treatment and until immune recovery.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.