About nusinersen sodium eq to nusinersen
Antisense oligonucleotide for spinal muscular atrophy
Used for
- Treats spinal muscular atrophy (SMA) in children and adults.
Usual adult dose
Intrathecal injection: 12 mg per dose; four loading doses, then one dose every four months.
Usual dose in children
Same dose and schedule as adults; given by intrathecal injection.
Common side effects
- Headache
- Back pain
- Vomiting
- Low platelet count or kidney problems
Important warnings
- Requires injection into the spinal fluid by trained clinicians.
- Blood and urine monitoring may be needed for bleeding or kidney problems.
- Spinal puncture complications can include headache, back pain, or infection.
Pregnancy
Human pregnancy data are limited; potential risks are not established.
Breastfeeding
It is unknown whether nusinersen passes into breast milk; effects on infants are unknown.
Interactions
- No clinically significant drug interactions are established.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.