About norepinephrine
Vasopressor; adrenergic agonist
Used for
- Raises blood pressure in severe acute hypotension, including septic shock.
Usual adult dose
Intravenous infusion, commonly started at 0.05–0.1 micrograms/kg/min and adjusted to blood pressure in a monitored setting.
Usual dose in children
Intravenous infusion, commonly 0.05–0.1 micrograms/kg/min, carefully adjusted by specialists in intensive care.
Common side effects
- Slow or irregular heartbeat
- Reduced blood flow to limbs or organs
- Headache or anxiety
- Tissue injury if infusion leaks outside the vein
Important warnings
- For intravenous infusion by trained staff with continuous blood-pressure and heart monitoring.
- Concentrate must be diluted according to product instructions before infusion.
- Correct low blood volume when possible; the medicine can worsen poor circulation.
- Extravasation can cause severe tissue damage.
Pregnancy
May be used for serious low blood pressure when clinically necessary; effects on uterine blood flow require consideration.
Breastfeeding
There is limited information; use for urgent treatment is generally brief and supervised.
Interactions
- Some anaesthetics can increase abnormal heart rhythms.
- MAO inhibitors and tricyclic antidepressants may intensify blood-pressure effects.
- Other blood-pressure-raising medicines can increase cardiovascular effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.