About nonacog alfa
Recombinant factor IX clotting factor
Used for
- Prevention and treatment of bleeding in haemophilia B
- Bleeding control during surgery in haemophilia B
Usual adult dose
Individualised by body weight, bleeding severity, and target factor IX level; commonly 40–60 IU/kg for major bleeding.
Usual dose in children
Individualised by body weight and bleeding severity; commonly 40–60 IU/kg for major bleeding. Children may need more frequent doses.
Common side effects
- Headache
- Dizziness
- Nausea
- Injection-site reactions
Important warnings
- Allergic reactions, including severe reactions, can occur.
- Inhibitory antibodies may reduce treatment effectiveness.
- Blood clots are possible, especially with risk factors.
- Seek urgent care for severe allergic symptoms or suspected clotting.
Pregnancy
Limited human data; use when clearly needed, with specialist assessment.
Breastfeeding
Unknown whether it passes into breast milk; use when clearly needed.
Interactions
- No important medicine interactions are well established.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.