About nitrofura ntoin
Nitrofuran antibiotic
Used for
- Treatment of uncomplicated urinary tract infections caused by susceptible bacteria
- Prevention of recurrent urinary tract infections in selected cases
Usual adult dose
For uncomplicated infection: 100 mg twice daily with food for 5 days; regimens vary by country and formulation.
Usual dose in children
For children aged 3 months and older: 5–7 mg/kg daily in four divided doses, usually for 5 days; specialist guidance is needed.
Common side effects
- Nausea, reduced appetite, or diarrhea
- Headache or dizziness
- Urine may turn dark yellow or brown
- Rare lung, liver, nerve, or blood-cell reactions
Important warnings
- Not suitable for kidney infection or bloodstream infection.
- Avoid in significant kidney impairment; kidney-function thresholds vary by local guidance.
- Long-term use can rarely cause lung or liver injury.
- Avoid in infants under 3 months and near delivery.
Pregnancy
May be used during pregnancy when appropriate, but avoid near delivery because of newborn blood-cell risks.
Breastfeeding
Generally compatible for healthy, full-term infants; avoid if the infant is under one month or has G6PD deficiency.
Interactions
- Antacids containing magnesium trisilicate can reduce absorption.
- Probenecid or sulfinpyrazone can increase toxicity and reduce urinary drug levels.
- Quinolone antibiotics may have reduced antibacterial effect when used together.
- May interfere with some urine glucose tests.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.