About nevirapine
Non-nucleoside reverse transcriptase inhibitor
Used for
- Treats HIV-1 infection in combination with other antiretroviral medicines.
Usual adult dose
Usually 200 mg once daily for 14 days, then 200 mg twice daily, with other HIV medicines.
Usual dose in children
Dose depends on age, weight, and formulation; specialist dosing is required.
Common side effects
- Rash
- Nausea or vomiting
- Headache
- Liver inflammation or injury
Important warnings
- Can cause severe, sometimes life-threatening skin reactions.
- Serious liver injury is most likely during the first 18 weeks.
- Requires liver-function monitoring, especially during treatment initiation.
- Does not cure HIV or prevent transmission.
Pregnancy
Can be used in pregnancy when clinically appropriate; treatment decisions require specialist review.
Breastfeeding
HIV can pass through breast milk; breastfeeding recommendations depend on local guidance and clinical circumstances.
Interactions
- Rifampicin and some seizure medicines can lower nevirapine levels.
- St John's wort can reduce its effectiveness.
- It can reduce hormonal contraceptive levels; discuss reliable contraception.
- May interact with other HIV medicines and medicines affecting liver enzymes.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.