About nerandomilast
Phosphodiesterase 4B inhibitor
Used for
- Treatment of idiopathic pulmonary fibrosis in adults
Usual adult dose
18 mg by mouth twice daily, with or without food.
Common side effects
- Diarrhea
- Nausea
- Decreased appetite
- Weight loss
Important warnings
- May cause weight loss; monitor body weight.
- Diarrhea and nausea can lead to dehydration.
- Use caution with moderate or severe liver impairment.
- Avoid strong CYP3A inhibitors and inducers.
Pregnancy
Human pregnancy data are insufficient; use only if potential benefit justifies potential risk.
Breastfeeding
It is unknown whether nerandomilast passes into human milk; effects on infants are unknown.
Interactions
- Strong CYP3A inhibitors may increase nerandomilast levels.
- Strong CYP3A inducers may reduce nerandomilast levels.
- CYP3A substrates may require monitoring for altered effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.