About nefopam hydrochloride
Non-opioid centrally acting analgesic
Used for
- Short-term relief of moderate to severe acute pain
Usual adult dose
Usually 20 mg by slow intramuscular injection or slow intravenous injection; may repeat every 4–6 hours. Maximum 120 mg daily.
Common side effects
- Nausea, dry mouth, dizziness, or sweating
- Fast heartbeat or palpitations
- Drowsiness, confusion, or agitation
- Urinary difficulty
Important warnings
- May cause seizures, especially in people with seizure disorders.
- Can increase heart rate and blood pressure.
- Avoid combining with monoamine oxidase inhibitors; check other medicines for interactions.
- Can cause drowsiness; alcohol may worsen this effect.
Pregnancy
Generally avoided during pregnancy unless clearly needed; human safety information is limited.
Breastfeeding
Usually avoided during breastfeeding because safety information is limited.
Interactions
- Monoamine oxidase inhibitors may cause serious reactions.
- Other medicines with anticholinergic effects can increase side effects.
- Alcohol and sedatives can worsen drowsiness.
- Medicines that increase seizure risk may raise the chance of seizures.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.