About naproxen
Nonsteroidal anti-inflammatory drug (NSAID)
Used for
- Relief of pain and inflammation from arthritis and other musculoskeletal conditions
- Short-term relief of acute pain, including menstrual pain
Usual adult dose
For arthritis, commonly 500 mg twice daily; for acute pain, dosing varies by condition and formulation.
Usual dose in children
For juvenile arthritis, commonly 10 mg/kg daily in two divided doses; clinician-directed dosing is required.
Common side effects
- Indigestion, heartburn, nausea, or stomach pain
- Dizziness or headache
- Fluid retention and raised blood pressure
- Stomach ulcer or bleeding
Important warnings
- Can cause serious stomach bleeding, ulcers, or perforation.
- May increase risk of heart attack or stroke, especially with prolonged use.
- Avoid with other NSAIDs; use caution with kidney disease, heart failure, or high blood pressure.
- Delayed-release tablets are not intended for rapid relief of acute pain.
Pregnancy
Avoid from 20 weeks unless specifically directed; avoid from 30 weeks because of fetal heart risks.
Breastfeeding
Small amounts enter milk; short-term use is generally considered compatible, but alternatives may be preferred for newborns.
Interactions
- Blood thinners and antiplatelet medicines increase bleeding risk.
- Other NSAIDs, including ibuprofen, increase adverse effects.
- ACE inhibitors, ARBs, or diuretics may worsen kidney function.
- Lithium and methotrexate levels may rise.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.