About mycophen olate mofetil
Immunosuppressant; inosine monophosphate dehydrogenase inhibitor
Used for
- Prevents organ rejection after kidney, heart, or liver transplant
Usual adult dose
Usually 1 g twice daily after kidney transplant, or 1.5 g twice daily after heart or liver transplant.
Usual dose in children
For kidney transplants, usually 600 mg/m² twice daily; maximum 1 g twice daily. Specialist supervision is required.
Common side effects
- Diarrhoea, nausea, vomiting, or abdominal pain
- Low white blood cell counts and increased infections
- Anaemia or other blood-cell disorders
- Higher risk of certain cancers with long-term immunosuppression
Important warnings
- Can cause miscarriage and severe birth defects; pregnancy prevention and testing are required.
- Do not donate blood during treatment or for six weeks afterward.
- Increased risk of serious infections, including viral infections.
- Requires regular blood tests; do not stop without transplant-team guidance.
Pregnancy
Can cause miscarriage and serious birth defects. Avoid during pregnancy unless no suitable alternative; strict pregnancy-prevention measures are required.
Breastfeeding
Breastfeeding is generally not recommended during treatment because of potential serious harm to the infant.
Interactions
- Antacids containing magnesium or aluminium can reduce absorption.
- Cholestyramine can reduce mycophenolate exposure.
- Live vaccines should be avoided during treatment.
- Other medicines affecting immune function or blood counts may increase risks.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.