About mycophen olate
Immunosuppressant; antimetabolite
Used for
- Prevents organ rejection after kidney, heart, or liver transplant
- Treats lupus nephritis in some countries or specialist settings
Usual adult dose
Transplant: usually 1 g twice daily; dose varies by organ and regimen.
Usual dose in children
Kidney transplant, ages 3 months and older: usually 600 mg/m² twice daily, maximum 1 g twice daily.
Common side effects
- Diarrhea, nausea, vomiting, or stomach pain
- Low white blood cells or anemia
- Infections, including serious infections
- Increased risk of certain cancers, including lymphoma and skin cancer
Important warnings
- Can cause miscarriage and severe birth defects; pregnancy prevention and testing are required.
- Do not substitute mycophenolate mofetil with mycophenolic acid without medical supervision.
- Do not donate blood during treatment and for at least six weeks afterward.
- Requires monitoring of blood counts and signs of infection.
Pregnancy
Can cause miscarriage and serious birth defects. Avoid during pregnancy unless no suitable alternative; strict pregnancy-prevention measures are required.
Breastfeeding
Breastfeeding is not recommended during treatment because of potential serious effects on the infant.
Interactions
- Antacids containing magnesium or aluminum can reduce absorption.
- Cholestyramine and some phosphate binders can reduce mycophenolate levels.
- Live vaccines may cause infection or work poorly.
- Other medicines that suppress immunity can increase infection and blood-cell problems.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.