About mirabegron
Beta-3 adrenergic agonist
Used for
- Treats overactive bladder symptoms, including urgency, frequent urination, and leakage.
- With solifenacin, treats overactive bladder in adults.
Usual adult dose
Usually 25 mg once daily; may increase to 50 mg once daily.
Usual dose in children
For neurogenic detrusor overactivity, usually 6 mg/m² once daily, up to 50 mg; specialist-directed.
Common side effects
- High blood pressure
- Urinary tract infection
- Headache
- Constipation
Important warnings
- Can raise blood pressure; monitor it during treatment.
- May cause urinary retention, especially with bladder outlet obstruction or other bladder medicines.
- Seek urgent care for facial swelling or difficulty breathing.
- Granules must be prepared and measured as directed; do not crush or chew.
Pregnancy
Human pregnancy information is limited; use only when the expected benefit outweighs potential risk.
Breastfeeding
It is unknown whether mirabegron passes into human milk; discuss potential risks and benefits.
Interactions
- Can increase digoxin levels; monitoring and dose adjustment may be needed.
- May raise levels of metoprolol and some other CYP2D6 substrates.
- Caution with medicines that prolong the QT interval.
- Other medicines that cause urinary retention can increase retention risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.