About mifepristone
Progesterone receptor blocker
Used for
- With misoprostol to end an early pregnancy.
- With misoprostol for pregnancy loss management, where approved.
Usual adult dose
Pregnancy termination: 200 mg once, followed 24–48 hours later by misoprostol, according to the approved regimen.
Common side effects
- Cramping and vaginal bleeding
- Nausea, vomiting, or diarrhea
- Headache or dizziness
- Fever or chills after misoprostol
Important warnings
- Use only under the required medical supervision and follow-up.
- Heavy bleeding or severe pain can require urgent care.
- Not suitable for ectopic pregnancy; it does not treat it.
- Seek medical assessment if pregnancy continues after treatment.
Pregnancy
Used to end pregnancy; it can cause pregnancy loss if taken unintentionally. It is not used to support an ongoing pregnancy.
Breastfeeding
Small amounts may enter breast milk. Guidance on breastfeeding interruption varies by regimen and local labeling.
Interactions
- Corticosteroids: may increase steroid effects or require dose adjustment.
- Rifampin, certain seizure medicines, and St John’s wort may reduce effectiveness.
- Anticoagulants may increase bleeding risk.
- Some antifungals and antibiotics can affect mifepristone levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.