About midazolam
Short-acting benzodiazepine sedative
Used for
- Sedation before procedures or surgery
- Sedation during procedures or intensive care
- Induction of general anesthesia
Usual adult dose
Varies by purpose and route; typically 1–2 mg IV increments for procedural sedation, adjusted carefully.
Usual dose in children
Specialist-determined, weight-based dosing; varies by age, route, and purpose.
Common side effects
- Drowsiness and impaired coordination
- Slow or shallow breathing
- Low blood pressure
- Confusion or memory problems
Important warnings
- Can cause severe breathing problems, especially with opioids or other sedatives.
- Requires close monitoring and trained staff during administration.
- Can cause dependence and withdrawal after prolonged use.
- Avoid alcohol; effects may persist after administration.
Pregnancy
May harm or sedate the fetus, particularly near delivery; use only when clinically necessary.
Breastfeeding
May cause infant sleepiness or poor feeding; monitor the infant after maternal use.
Interactions
- Opioids and other sedatives increase breathing suppression.
- Some antifungals, antibiotics, and antivirals can increase midazolam effects.
- Carbamazepine, phenytoin, and rifampicin can reduce its effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.