About metronidazole benzoate
Nitroimidazole antibiotic and antiprotozoal
Used for
- Treats amoebiasis and giardiasis.
- Treats certain anaerobic bacterial infections.
- Treats trichomoniasis when an appropriate oral formulation is prescribed.
Usual adult dose
Varies by infection; commonly 500–750 mg by mouth three times daily for amoebiasis, or 250 mg three times daily for giardiasis, for several days.
Usual dose in children
Dose depends on infection and weight; commonly 35–50 mg/kg/day in divided doses for amoebiasis, or 15 mg/kg/day for giardiasis. A clinician determines duration and maximum dose.
Common side effects
- Nausea, vomiting, diarrhoea, or abdominal discomfort
- Metallic taste or reduced appetite
- Headache or dizziness
- Dark urine
Important warnings
- Avoid alcohol during treatment and for at least 48 hours afterward.
- Seek medical assessment for numbness, tingling, seizures, or severe rash.
- Use caution with liver disease or prolonged treatment.
- Complete the prescribed course; dosing depends on the specific infection.
Pregnancy
Use depends on the infection and pregnancy stage; treatment should be guided by a healthcare professional.
Breastfeeding
Metronidazole passes into breast milk. Advice depends on dose and treatment duration; consult a healthcare professional.
Interactions
- Warfarin and other coumarin anticoagulants: may increase bleeding risk.
- Lithium: levels may rise.
- Disulfiram: concurrent use may cause mental reactions.
- Alcohol or propylene glycol: may cause unpleasant reactions.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.