About metronidazole spiramycin mui
Nitroimidazole antibiotic plus macrolide antibiotic
Used for
- Treatment of certain mouth and dental infections caused by susceptible bacteria.
Usual adult dose
Commonly, 4–6 tablets daily in divided doses; follow local product guidance.
Usual dose in children
Used for some children; dosing depends on age and weight and requires clinician guidance.
Common side effects
- Nausea, stomach pain, diarrhea, or vomiting
- Metallic taste or dry mouth
- Headache or dizziness
- Rash or allergic reaction
Important warnings
- Avoid alcohol during treatment and for at least 48 hours afterward.
- May interact with warfarin and other medicines; interaction checks are important.
- Seek urgent care for severe rash, numbness, or unusual coordination problems.
- Use only for infections where this combination is appropriate.
Pregnancy
Use only when considered necessary by a clinician; pregnancy-specific risks should be assessed.
Breastfeeding
Metronidazole and spiramycin can enter breast milk; seek clinician guidance before use.
Interactions
- Warfarin and other anticoagulants may increase bleeding risk.
- Disulfiram may cause serious mental effects with metronidazole.
- Lithium levels may rise with metronidazole.
- Alcohol may cause an unpleasant reaction during treatment and shortly afterward.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.