About Metronidazole 0.5% W/V
Nitroimidazole antibiotic and antiprotozoal
Used for
- Treats serious infections caused by susceptible anaerobic bacteria
- Treats certain protozoal infections, including amoebiasis
Usual adult dose
Usually 500 mg intravenously every 8 hours; dose and duration depend on infection and kidney or liver function.
Usual dose in children
Usually 7.5 mg/kg intravenously every 8 hours; maximum 500 mg per dose. Specialist guidance is needed.
Common side effects
- Nausea, vomiting, or diarrhea
- Metallic taste or reduced appetite
- Headache or dizziness
- Infusion-site irritation
Important warnings
- Avoid alcohol during treatment and for at least 48 hours afterward.
- Seek medical assessment for numbness, tingling, seizures, or severe rash.
- Use cautiously with significant liver disease or blood disorders.
- Use only for susceptible infections; unnecessary use promotes antibiotic resistance.
Pregnancy
Use when clearly needed; treatment decisions depend on infection and pregnancy stage.
Breastfeeding
Metronidazole enters breast milk. Clinicians may advise timing feeds around treatment, especially after high doses.
Interactions
- Warfarin and similar anticoagulants: increased bleeding risk
- Lithium: potentially increased lithium levels
- Disulfiram: possible confusion or psychotic reactions
- Alcohol: may cause unpleasant reactions
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.