About methylpre dnisolone hemi
Systemic corticosteroid
Used for
- Severe allergic reactions
- Severe asthma attacks
- Inflammatory and autoimmune disease flare-ups
- Multiple sclerosis relapses
Usual adult dose
Usually 10–40 mg initially by intravenous or intramuscular injection; subsequent doses depend on the condition. Severe conditions may require higher doses.
Usual dose in children
Often 0.5–2 mg/kg daily intravenously, in divided doses; dose and duration depend on the condition.
Common side effects
- Increased blood sugar
- Fluid retention and increased blood pressure
- Stomach upset
- Sleep disturbance and mood changes
Important warnings
- Increases infection risk and may hide infection symptoms
- Generally avoided with systemic fungal infections
- Live vaccines may be unsafe during immunosuppressive treatment
- Prolonged treatment requires gradual withdrawal
Pregnancy
May be used when benefits outweigh risks. Prolonged treatment may affect fetal growth or newborn adrenal function.
Breastfeeding
Small amounts enter breast milk. Usually compatible; high intravenous doses may require a temporary breastfeeding pause.
Interactions
- Ibuprofen and aspirin increase stomach bleeding risk
- Warfarin effects may change
- Diabetes medicines may require dose adjustments
- Rifampicin and some antifungals alter methylprednisolone levels
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.