About methylergometrine
Ergot alkaloid uterotonic
Used for
- Prevents or treats heavy bleeding after childbirth by helping the womb contract.
Usual adult dose
Usually 0.2 mg by intramuscular injection; repeat every 2–4 hours if needed. Intravenous use is reserved for emergencies and given slowly.
Common side effects
- Nausea or vomiting
- Headache or dizziness
- Raised blood pressure
- Abdominal cramping
Important warnings
- Do not use during pregnancy before delivery.
- Avoid in high blood pressure, pre-eclampsia, or significant heart or blood vessel disease.
- Intravenous injection can cause sudden severe high blood pressure or stroke; use only when necessary.
- Use cautiously with liver or kidney problems.
Pregnancy
Contraindicated before delivery because it can cause strong uterine contractions. Used after childbirth for bleeding.
Breastfeeding
May reduce milk production and pass into breast milk. Repeated use is generally avoided during breastfeeding.
Interactions
- Strong CYP3A4 inhibitors, including clarithromycin and ritonavir, may cause dangerous ergot toxicity.
- Other ergot medicines increase toxicity risk.
- Other medicines that raise blood pressure may increase severe hypertension risk.
- Some anaesthetics, including halothane, may increase blood vessel constriction.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.