About methoxamine hydrochloride
Direct-acting alpha-1 adrenergic agonist
Used for
- Raises blood pressure during certain types of low blood pressure, including anesthesia-related hypotension.
Usual adult dose
Given by a healthcare professional, usually as a slow intravenous injection; dose is adjusted to blood pressure response.
Common side effects
- High blood pressure
- Slow heartbeat
- Headache
- Nausea or vomiting
Important warnings
- Can cause dangerously high blood pressure or a markedly slow heartbeat.
- Use requires close monitoring of blood pressure and heart rhythm.
- May reduce blood flow to the heart, brain, kidneys, or limbs.
- Use caution with heart disease, high blood pressure, or poor circulation.
Pregnancy
Use only when clearly needed; human pregnancy safety information is limited.
Breastfeeding
Information is limited; use cautiously under medical supervision.
Interactions
- Other medicines that raise blood pressure may increase hypertension risk.
- Monoamine oxidase inhibitors may intensify blood-pressure effects.
- Ergot medicines may increase blood-vessel constriction.
- Atropine may worsen the slow-heartbeat response.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.