About metformin hcl + vildagliptin
Biguanide and DPP-4 inhibitor combination
Used for
- Type 2 diabetes, alongside diet and exercise
Usual adult dose
Usually one tablet twice daily with meals; dose depends on prior treatment and kidney function.
Common side effects
- Nausea, diarrhoea, or abdominal discomfort
- Headache or dizziness
- Low blood sugar, especially with insulin or sulfonylureas
- Rarely, pancreatitis or liver problems
Important warnings
- Not for type 1 diabetes or diabetic ketoacidosis.
- Metformin can rarely cause serious lactic acidosis; risk rises with severe kidney problems or acute illness.
- Check kidney function before and during treatment; avoid in severe kidney impairment.
- Vildagliptin can affect the liver; liver tests are recommended before treatment and periodically.
Pregnancy
Not generally recommended; diabetes treatment in pregnancy should be clinician-supervised.
Breastfeeding
Not generally recommended because information on both medicines during breastfeeding is limited.
Interactions
- Alcohol increases the risk of metformin-associated lactic acidosis.
- Insulin or sulfonylureas increase low-blood-sugar risk.
- Some medicines affect kidney function or metformin levels; examples include contrast dyes and cimetidine.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.