About mesalamine m
Aminosalicylate anti-inflammatory
Used for
- Inducing and maintaining remission in ulcerative colitis
- Treating mild-to-moderate Crohn’s disease in some settings
Usual adult dose
Ulcerative colitis: usually 2–4 g daily, divided doses; dose depends on disease activity.
Usual dose in children
For ulcerative colitis, usually 50–75 mg/kg daily in divided doses; maximum 4 g daily.
Common side effects
- Headache
- Abdominal pain, nausea, or diarrhoea
- Rash
- Rarely, kidney inflammation or blood disorders
Important warnings
- Kidney function should be checked before and during treatment.
- Stop and seek urgent assessment for severe rash, breathing difficulty, or unusual bruising.
- Report worsening abdominal pain, bloody diarrhoea, or fever.
- Avoid with salicylate allergy; use caution with kidney disease.
Pregnancy
Use only when considered necessary; untreated ulcerative colitis also carries risks. Discuss treatment with a clinician.
Breastfeeding
Small amounts enter breast milk; diarrhoea in the infant has been reported. Monitor for symptoms.
Interactions
- Azathioprine or mercaptopurine: increased risk of blood disorders.
- Warfarin: mesalazine may affect anticoagulant control.
- Other medicines that can affect the kidneys may increase kidney risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.