About meroprnr m
Carbapenem antibiotic
Used for
- Serious bacterial infections, including pneumonia
- Complicated abdominal infections
- Complicated urinary tract infections
- Bacterial meningitis
Usual adult dose
Usually 500–1,000 mg intravenously every eight hours; meningitis may require 2,000 mg every eight hours. Lower doses are needed with kidney impairment.
Usual dose in children
Age three months and older: usually 10–20 mg/kg intravenously every eight hours; meningitis: 40 mg/kg every eight hours, maximum 2,000 mg per dose.
Common side effects
- Diarrhea, nausea, or vomiting
- Headache
- Skin rash
- Pain or inflammation at the injection site
Important warnings
- May cause serious allergic reactions, especially with previous beta-lactam antibiotic allergy
- Seizures can occur, especially with kidney impairment or seizure disorders
- Severe or persistent diarrhea may indicate antibiotic-associated bowel infection
- Kidney impairment requires dose adjustment
Pregnancy
Human pregnancy data are limited; use when the expected benefit outweighs potential risks.
Breastfeeding
Small amounts enter breast milk; generally considered compatible, but infant diarrhea or thrush may occur.
Interactions
- Valproate: substantially lowers levels, potentially causing breakthrough seizures
- Probenecid: increases meropenem levels
- Warfarin: may increase anticoagulant effects; additional monitoring may be needed
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.